All About Daily Colorado Springs News

How Psilocybin Works - And Why It's Being Studied By Premier Universities

Jun 23


Psilocybin, the main component in magic mushrooms, has been making headlines lately. The substance is being studied for its potential to treat a range of mental health conditions from PTSD and depression to anxiety disorders. While most people probably associate these psychedelic fungi with hippies and Grateful Dead concerts, psilocybin may actually be one of the safest drugs out there—and it could help millions of people around the world experience some pretty amazing benefits.

Psilocybin main component of magic mushrooms

Psilocybin is the main psychoactive component of magic mushrooms, and it's what gives these fungi their psychedelic kick.

The drug was first synthesized in 1958 by Albert Hofmann, who discovered its hallucinogenic properties five years later. Since then, psilocybin has been studied extensively by scientists as a means to treat anxiety and depression—and yes, even addiction. In fact, many top universities like Johns Hopkins and Harvard are currently looking into how psilocybin could actually help people overcome addiction.

Psilocybin can be found in some other plants besides magic mushrooms (like certain species of psychedelic cacti), but there have been no studies on those other types of compounds yet—so for now we'll focus on psilocybin-containing mushrooms only!

How psilocybin works on the brain

The primary mode of action seems to be psilocybin’s interaction with serotonin receptors in the brain. Serotonin is a neurotransmitter that plays an important role in mood and behavior, so it makes sense that this chemical would play a key role in how people respond to psilocybin. However, the drug doesn't just act on serotonin receptors—it also affects dopamine receptors, which are involved in regulating movement, motivation and addiction behaviors.

While some psychedelics such as LSD (lysergic acid diethylamide) have been shown to act as agonists at serotonin receptors (meaning they bind directly with them), psilocybin appears instead to act as an indirect agonist or partial agonist at these receptor sites by increasing levels of serotonin available within synapses between neurons.

Psilocybin can lead to positive personality change.

Psilocybin can lead to positive personality change.

In a study published in the Journal of Psychopharmacology, researchers found that participants who used psilocybin showed improved well-being and life satisfaction scores. They also reported lower anxiety, depression, and death anxiety scores than those who received a placebo.

The researchers hypothesize that this may be due to psilocybin’s ability to improve self-perception by creating “a sense of connection with nature or a sense of unity with all things.”

Psilocybin may help PTSD and depression.

Psilocybin has been shown to help people with PTSD, depression and anxiety. The drug is not FDA-approved, but some researchers are working tirelessly to get it into clinical use as soon as possible.

In the meantime, there are plenty of studies being conducted by respected universities like Johns Hopkins University and NYU Langone School of Medicine that focus on how psilocybin can be used to treat mental illnesses.

Psilocybin is being studied by top universities.

Psilocybin, the active ingredient in magic mushrooms, is being studied at some of the top universities in the country. Harvard, Johns Hopkins and UCLA are just a few examples of premier institutions that are researching psilocybin's therapeutic potential.

Because it has been illegal since 1970, this new area of research is largely unexplored and untapped. But as legalization efforts move forward and more studies are conducted on humans instead of rats or mice (like those done at John Hopkins), we may see new treatments for depression and PTSD on the horizon.

There are some surprising benefits from using psilocybin mushrooms in a controlled setting.

Psilocybin is the main psychoactive ingredient in magic mushrooms, and it seems to have some surprising benefits when used in a controlled setting. It's an active chemical in the brain that works on receptors in your brain similar to how LSD does. Scientists have studied its effects on mice, but they're now also studying its effects on humans through studies at top universities like Johns Hopkins University and New York University.

The reason psilocybin is being studied by these premier institutions is because there are some promising results of using psilocybin mushrooms for treating anxiety disorders and depression. There was one study done on 17 people who had never taken psychedelic drugs before; these people were given two doses of psilocybin each day for six weeks straight at NYU Langone Medical Center. At the end of this period all participants showed significant improvement from their baseline states when it came to depression scores—meaning they felt less depressed than before taking part in this experiment!


Psilocybin is a powerful psychedelic, but it can also help people with depression and PTSD. While it’s still not approved by the FDA for medical use, there are many studies being conducted on whether psilocybin could be used as an effective treatment. We hope that you’re intrigued by this new drug and want to learn more about its potential benefits and risks.